Two new compounds from the marine Nigrospora sphaerica.

Two new compounds, 1-(5-oxotetrahydrofuran-2-yl)ethyl 2-phenylacetate (1) and 3-hydroxybutan-2-yl 2-hydroxy-3-phenylpropanoate (2), along with three known compounds, harzialactone A (3), benzeneethanol 4-hydroxy-1-acetate (4), and 1,4-dioxane-2,5-dione-3,6-bis(penylmethyl)-homopolymer (5), have been isolated from the fungus Nigrospora sphaerica. Their structures were determined on the basis of chemical and spectroscopic methods.