A prospective, randomized, blind comparison between saline, calcium gluconate and diphoterine for washing skin acid injuries in rats: effects on substance P and β-endorphin release

SummaryBackground and objective:A randomized, blind study to evaluate the effects on β-endorphin and substance P release after washing acid burns with 0.9% saline, calcium gluconate or diphoterine in a model of chemical burn in rats.Methods:Twenty Sprague-Dawley rats (approximate weight 250 g) were