Purification of placental anemia inducing factor (PAIF) and its clinical application by radioimmunoassay

Human Placental Anemia Inducing Factor (PAIF) was purified from crude placental preparation called P-62, which had common biological and immunological natures with the same preparation from gastric juice, gastric tissues, serum and urine of patients with malignant neoplasma, especially gastric cancer1-4). The obtained PAIF was homogeneous on polyacrylamide gel electrophoresis and gave a specific band in the region of γ-A and/or γ-M globulin on immunoelectrophoresis.