Anti-Fatigue Activity of Honey From Apis mellifera, Apis cerana, and Trigona sp in Mice

Fatigue is a major factor in the decline in the quality and quantity of the athlete's performance. The cause of fatigue is the accumulation of lactic acid in the muscles. This is caused by the body's ability to neutralize lactic acid is not proportional to the speed of lactic acid formed by the severity of sports activities undertaken, if it lasts long, it will interfere with the performance. In the present study, we investigated the anti-fatigue activity in male mice of honey from Apis mellifera (HAM), Apis cerana (HAC), and Trigona sp (HT) using a forced swimming test. Mice were divided into four groups (three honey administered groups and the control group). The control group were gave with distilled water and honey administered groups were gave with honey (1,14 g/ body weight). After three weeks, a forced swimming test was performed and the biochemical parameters related to fatigue were examined. The results suggested that honey could extend the swimming time to exhaustion of the mice, as well as increase the tissue glycogen contents, while decreasing the blood lactate and maintaning blood glucose level. This indicated that honey had anti-fatigue activity and could elevate the exercise tolerance.