Regio- and Stereospecificity in Radical Cascade Cyclizations of TMS-Alcyne Containing Allyl Bromomethyldimethylsilyl Ethers.

Abstract Tandem radical cyclization of (E) and (Z) TMS-homopropargyl allyl bromomethyl-dimethylsilyl ethers is reported to provide an all- cis substituted vinylcyclopentanol 5 . Regio- and stereospecificity are discussed.