Transcriptional Upregulation of Breast Cancer Resistance Protein by 17β-Estradiol in ERα-Positive MCF-7 Breast Cancer Cells

Yuhua Zhang,Gengyin Zhou,Huaiping Wang,Xiaofang Zhang,Fulan Wei,Yongping Cai,Deling Yin

Transcriptional Upregulation of Breast Cancer Resistance Protein by 17β-Estradiol in ERα-Positive MCF-7 Breast Cancer Cells

2006

Yuhua Zhang
Gengyin Zhou
Huaiping Wang
Xiaofang Zhang
Fulan Wei
Yongping Cai
Deling Yin

Objectives: Breast cancer resistance protein (BCRP) confers resistance to certain anticancer drugs such as mitoxantrone, topotecan and SN-38. A putative estrogen response element (E

Keywords:

Immunology
Estrogen
Abcg2
Cancer
Topotecan
Breast cancer
Estrogen receptor
Mitoxantrone
Cancer research
Medicine
MCF-7
Downregulation and upregulation

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