Susceptibility to Measles Among Perinatally HIV-Infected Adolescents and Young Adults

Among our cohort of adolescents and young adults with perinatally acquired human immunodeficiency virus, few (17.6%) had measles protective antibodies by plaque reduction neutralization (PRN). Agreement was demonstrated between the commercial enzyme immunoassay and the PRN assay (K = 0.59 [95% confidence interval: 0.23–0.95]). Further studies are needed to understand the determinants of immunity in this population.