Adrenoceptors on blood cells in patients with primary hypertension : correlation with blood pressure and related variables

Objective: Alterations in platelet α 2 -adrenoceptor and mononuclear leucocyte α 2 -adrenoceptor characteristics in primary hypertension have been extensively studied. The results of the reports have not been consistent, possibly because of the small number of subjects in most of the studies. We therefore studied the blood-cell adrenoceptor characteristics in a relatively large group of primary hypertensive and normotensive subjects, Design: Platelet α 2 -adrenoceptor characteristics were compared in 65 hypertensive and 51 normotensive subjects. Mononuclear leucocyte β 2 -adrenoceptor characteristics were compared in 72 hypertensives and 67 normotensives