Aminomethyl substituted thieno[2,3- d ]pyrimidines as adenosine A2A receptor antagonists
2011
A novel series of aminomethyl substituted thieno[2,3-d]pyrimidines have been identified as adenosine A2A receptor antagonists. Analogues show excellent in vitro activities and have excellent activity in vivo in mouse models of Parkinson's disease.
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