Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects

Dipender Gill,Marios K. Georgakis,Fotios Koskeridis,Lan Jiang,QiPing Feng,Wei-Qi Wei,Evropi Theodoratou,Paul Elliott,Joshua C. Denny,Rainer Malik,Evangelos Evangelou,Abbas Dehghan,Martin Dichgans,Ioanna Tzoulaki

Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects

2019

Dipender Gill
Marios K. Georgakis
Fotios Koskeridis
Lan Jiang
QiPing Feng
Wei-Qi Wei
Evropi Theodoratou
Paul Elliott
Joshua C. Denny
Rainer Malik
Evangelos Evangelou
Abbas Dehghan
Martin Dichgans
Ioanna Tzoulaki

Background: Drug effects can be investigated through natural variation in the genes for their protein targets. The present study aimed to use this approach to explore the potential side effects and...

Keywords:

Antihypertensive drug
Drug
Diabetes mellitus
Internal medicine
Cardiology
Side effect
Bioinformatics
Medicine
genetic variants
Gene
Mendelian randomization
Genome-wide association study
Mendelian Randomization Analysis
Disease

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