Wheezing and Infantile Colic Are Associated With Neonatal Antibiotic Treatment

BC Oosterloo, RM van Elburg, NB Rutten. Pediatr Allergy Immunol. 2018;29(2):151–158 The authors of the Intestinal Microbiota Composition After Antibiotic Treatment in Early Life study examined the effect of antibiotics given during the first week of life on the development of atopic disease and infantile colic (as well as other nonatopic disease). They also studied whether the development of these conditions depends on the duration of antibiotics. An observational birth cohort of term infants (>36 weeks’ gestation) were recruited from 4 Dutch teaching hospitals. AB- infants were healthy untreated controls, whereas AB+ infants received broad-spectrum antibiotics. AB2 received antibiotics for 2 to 3 days (low suspicion for neonatal infection), and AB7 received antibiotics for 7 …