Pd/C-Catalyzed Hydrogenation of Substituted 5-Acyl-1,3-dioxanes

Hydrogenation of substituted 5-acyl-1,3-dioxanes in the presence of a Pd/C catalyst leads to the formation of substituted 1,3-dioxane alcohols as the only reaction products. The effect of a number of factors (temperature, rate of hydrogen and substrate supply) on the conversion of the ketone and the selectivity of the formation of alcohol was investigated.