Abstract P177: The Impact of Triple Therapy (3T) as Secondary Prevention for Recurrent Acute Coronary Syndrome Patients With Prior Myocardial Infarction

Background: We determined if use of aspirin, beta-blocker, and statin, or triple therapy (3T), on admission for recurrent acute coronary syndromes (ACS) improved outcomes in patients with history of myocardial infarction (MI). Methods: A total of 1442 patients with history of MI who presented with ACS between January 1999 and December 2006 were identified. Data on baseline demographics, clinical presentation, and in-hospital management were collected, and patients with contraindications to any of the three drugs were excluded. Patients were then separated into two groups based on presence or absence of 3T in admission medications. The impact of 3T on in-hospital, 6-month, and 2-year mortality and adverse cardiovascular events was then analyzed using Pearson Chi-Square tests, Student's t-tests, and multivariate logistic regression. Results: Only 42.3% (610 of 1442) patients were found to be taking 3T upon admission. These patients were more likely to be younger and to have a history of previous PCI or CABG...