Characterization of Cas9–Guide RNA Orthologs

Jonathan L. Braff,1,4 Stephanie J. Yaung,1,2,3,4 Kevin M. Esvelt,1 and George M. Church1,2,5 Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, Massachusetts 02115; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115; Program in Medical Engineering and Medical Physics, Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139