Chemical Composition, Antioxidant and Anti-bacterial Potential of Essential Oil of Medicinal plant Isodon rugosus

AbstractIsodon rugosus is a medicinally valuable herb containing a variety of important secondary metabolites and essential oil with important chemical constituents of pharmaceutical precursors. The active components of volatile oil of I. rugosus were analyzed using GC-MS. Anti-oxidant potential of the oil was assessed with 2, 2-diphenyl-1-picrylhydrazyl (DPPH). Anti-bacterial power of the essential oil accessed disc diffused method. A total of 19 constituents were quantified and identified with different concentrations in essential oil. Among which Caryophyllene oxide was 28.99%. Limonene oxide cis was 26.52%, (Z, E)-Farnesol was 17.34%, followed by 1-erpinen-4-ol 3.33%, o-Cymene 2.04 while the concentrations of rest of constituents were between 1.11 to 0.2%. The investigation showed that the essential oil of I. rugosus possessed significant antibacterial and antioxidant potential