Macular pigment optical density assessment in monozygotic and dizygotic twins

Abstract.The purpose of the study. To determine macular pigment optical density (MPOD) within pairs of monozygotic (MZ) twins and dizygotic (DZ) twins. Thirty MZ twins and fourteen DZ opthalmologically healthy twins were tested. MZ and DZ twins were matched by age and gender. The optional macular pigment density module for the Visucam 500 used the reflectance of a single 460-nm wavelength based on a single blue-reflection fundus image to determine MPOD and its spatial distribution. The median of macular pigment optical density were 0.102 for MZ twins vs 0.104 for DZ twins, respectively, p=0.541. Our results revealed that there were statistically significant difference between left and right eyes in monozygotic and dyzigotic twins.