Solitary Fibrous Tumor of the Liver

Solitary fibrous tumor of the liver is a rare neoplasm. Thirty-nine cases have been described in the English literature. Its immunohistochemical positivity for CD34 and vimentin is believed to be unique. It is known to be usually benign and only one case of metastasis is reported. We report an additional case. A 71-year-old woman presented with fatigue and weight loss. CT scan showed a solid mass occupying the left lobe of the liver. Left lobectomy was performed. Pathological examination showed spindle cell and fibroblast-like cells within the collagenous stroma. On immunohistochemical staining, these spindle tumor cells showed diffuse CD34 and vimentin positive reactivity. The post-operative course was uneventful. Solitary fibrous tumors of the liver, although rare, need to be considered in the differential diagnosis of mesenchymal lesions of the liver.