The Impact of Ethnicity, Language, and Anxiety on Quality of Life in Children with Cancer

Undergoing cancer treatment significantly impacts quality of life (QOL). This study evaluated the role of anxiety, ethnicity, and language on QOL in children with a cancer diagnosis. Participants included 156 parent–child dyads in 3 groups: English-speaking Hispanic, Spanish-speaking Hispanic, and English-speaking non-Hispanic White. Parents completed measures of self-reported anxiety and their children’s perceived QOL. Children completed self-reported measures of anxiety and QOL. Families in which parents primarily spoke English reported higher parent-reported generic-module QOL (p = 0.0062), higher parent-reported cancer-specific QOL (p = 0.004), lower parent trait anxiety (p = 0.0005)), and lower child trait anxiety (p = 0.013), compared to families in which parents primarily spoke Spanish. Regression analyses were strongly supportive of a mediational role of parent trait anxiety in the association of ethnicity/language and parent-reported QOL. The results of this study suggest that children of Spanish-speaking parents may be at greater risk of decreased quality of life, as a function of increased parental anxiety.