Disquisition on the interaction of ibuprofen–Zn(II) complex with calf thymus DNA by spectroscopic techniques and the use of Hoechst 33258 and Methylene blue dyes as spectral probes

GRAPHICAL ABSTRACTa) Hoechst interaction with DNA and its spectrab) Competitive interaction of Zn-ibuprofenato complex and Hoechst with DNAc) The Zn-ibuprofenato complex competes against Hoechst in binding with DNA and excludes the Hoechst from the duplex, so the concentration of Hoechst binding with DNA reduces