Pigmented lichenoid drug eruption: a new clinical presentation of interface dermatitis induced by anti-TNF alpha drugs.

Anti-tumour necrosis factor alpha (TNFα) therapies are used in several inflammatory diseases. A wide range of adverse events has been reported in patients receiving these agents, including lupus-like syndrome, lichen planus, or psoriasiform eruption [1], all comprising, histologically, a lichenoid interface dermatitis. It is commonly accepted that lichenoid eruptions are associated with increased expression of type I interferon (IFN) [2, 3]. Here, we report a novel clinical presentation of pigmented [...]