BACTERIAL PATHOGENS WITH MULTIDRUG RESISTANCE. ETIOLOGICAL STRUCTURE OF INFECTIONS IN ICU, UMBAL-EAD

High prevalence of resistance leads to increased antibiotic prescripting which results in extra costs and further emergence of new resistance mechanisms. In addition, such high prevalence might well contribute to increased morbidity and extra-incidence of nosocomial infections The aim of the present report is to determine the etiological structure of the infections in patients in ICU and their frequency of transmission of MDROs; determination of the mechanisms of phenotypic resistance of the most frequent isolates with epidemiological value.. Our analysis has been performed for the period 20042008.We have investigated 1129 different materials. Conventional methods have been used for isolation of bacterial pathogens. The antimicrobial susceptibility testing has been performed by Disk Diffusion Method with different antimicriobial agents. In conclusion, we could say that MDROs are mostly among Gram negative bacilli-P. aeruginosa, E. coli, A. baumannii. E. coli , producing ESBLs are 18%;group KES (Klebsiella, Enterobacter, Serratia), producing ESBLs are 27%. Carbapenems are effective to ESBLs producing Enterobacteriaceae.MRSA are 21%.