Synthesis of enantiopure aminonaphthol derivatives under conventional/ultrasonic technique and their ring-closure reaction
2016
Abstract New optically active aminoalkylnaphthols were obtained by condensation of 2-naphthol, substituted aromatic and heteroaromatic aldehydes and ( R )-(+)-1-phenylethylamine or ( S )-(−)-1-phenylethylamine under conventional methods and ultrasonic irradiation. The enantiopure aminoalkylnaphthol derivatives were converted in ring-closure reaction with formaldehyde to the corresponding naphthoxazine derivatives.
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