Heterotopic ossifications after longterm weaning due to COVID-19

While pneumological, cardiovascular and neurological complications of a SARS-CoV-2 infection are already well researched, relatively little is known about influences on the musculoskeletal system The case of a 65-year-old patient is reported who suffered a fracture of the humeral head that was treated conservatively Six weeks after injury he developed cough and temperature and CoVID-19 was diagnosed He developed a severe course of COVID-19 with ARDS, pulmonary artery embolism, multiple strokes und left-sided hemiparesis, requiring artificial respiration for several weeks Subsequently, pronounced ossifications developed around the left shoulder and the left elbow Heterotopic ossifications after craniocerebral trauma, after spinal cord injuries or long-term artificial respiration are known Further research is still needed to answer the question whether the heterotopic ossifications are caused by proinflammatory processes due to immobilisation and long-time artificial respiration or by still unknown pathomechanisms as a direct consequence of SARS-CoV-2