A Review on Magnesium-based Materials for Bone Applications

The use of biodegradable metallic-based material for bone applications as an implant as well for scaffolding purposes have been increasing significantly. The interest on biodegradable bone implant materials are driven from the increasing knowledge on biomedical materials and tissue engineering field to some positive clinical findings. Various biodegradable polymeric- and metallic-based materials have been used for bone screw, for instant. Biodegradable materials also desirable feature for bone scaffold application since the goal is that it uses as a temporary structure holding a growing bone tissues until the bone defect healed. Magnesium has a potential chance to serve as biodegradable bone implant material, as it has mechanical properties similar to natural bone, lightweight, and biocompatible approved. This article aims to report current development and future potential use of magnesium-based metal for bone implant application. Techniques on manufacturing process, mechanical performance, and biocompatibility assessment of magnesium and its alloys will also highlight.