The Impact of Placebo Response Rates on Clinical Trial Outcome: A Systematic Review and Meta-Analysis of Antidepressants in Children and Adolescents with Major Depressive Disorder

Yanfei Li,Jihan Huang,Yingchun He,Juan Yang,Yinghua Lv,Hongxia Liu,Liyu Liang,Huafang Li,Qingshan Zheng,Lujin Li

The Impact of Placebo Response Rates on Clinical Trial Outcome: A Systematic Review and Meta-Analysis of Antidepressants in Children and Adolescents with Major Depressive Disorder

2019

Yanfei Li
Jihan Huang
Yingchun He
Juan Yang
Yinghua Lv
Hongxia Liu
Liyu Liang
Huafang Li
Qingshan Zheng
Lujin Li

Abstract Objective: The high placebo response rate may hamper the discovery of antidepressants in children and adolescents with major depressive disorder (MDD). The aim of the study was to clarify ...

Keywords:

Clinical psychology
Clinical trial
Psychology
Psychiatry
Placebo
Meta-analysis
Major depressive disorder
placebo response
Systematic review

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