Carcinoma de Paratireóide

Parathyroid carcinoma is an uncommon malignancy. It accounts for less than 1% of cases of primary hyperparathyroidism. It is manifested by severe hypercalcemia and up to 50% of patients will have concomitant kidney or bone disease. Case Report: In this paper we reported a case of parathyroid carcinoma in a 46 year old woman with elevated parathyroid hormone level, with kidney insufficiency and suspected tertiary hyperparathyroidism. Conclusion: The etiology of parathyroide carcinoma is unknown. The preoperative differential diagnosis between parathyroid carcinoma and primary hyperparathyroidism is often difficult because many of the signs and symptoms are very similar. The optimal surgical treatment is en bloc tumor resection with ipsilateral thyroid lobectomy. The course of patients with parathyroid carcinoma is variable. More than 50% have persistent or recurrent disease due to regional or distant disease.