ANTI-ALLERGIC CELLULOSE SUPPORT AT THE EPIDERMIS- ENVIRONMENT INTERFACE

This paper is part of a study on the development and design of some cellulose articles intended for certain cutaneous allergic diseases: contact dermatitis (CD) and atopic dermatitis (AD). The study is based on the utilization of 100% cotton supports grafted with a cyclodextrin product, namely monochlorotriazinyl-beta-cyclodextrin (MCT-β-CD), for the inclusion of some natural active principles (AP), such as Viola tricoloris Herba (VTH), menthol (Ml) and propolis (Pr) ,with anti-allergic properties. The cellulose support addressing patients with cutaneous affections realizes a system for the transdermal controlled release of the AP from the cavities of the cyclodextrin grafted on the cellulose support, to the hypoderm level of the skin. In order to highlight the grafting with cyclodextrin reactive product and the inclusion of anti-allergic AP, the cellulose support was characterized by Fourier transform infrared spectroscopy (FTIR) measurements and nitrogen elemental analysis, while the morphological formations were rendered evident through scanning electron microscopy (SEM). The humidity profile and conduction were determined by the utilization of a liquid miming the perspiration transfer through the textile material treated with anti-allergic AP, as compared to a standard.