Effect of Nano-Selenium on Growth Performance and Immune Function of Weanling pigs

A total of 234 weaning pigs(Duroc×Landrace ×Yorkshire) at an average initial body weight of 8.3kg were allocated to 13 treatments,each of which had 3 pens of 6 pigs per pen.The thirteen dietary treatments were basal diet only(containing 0.04 mg/kg Se),basal diet + 0.1、0.2、0.3、0.4、0.5、1.0 mg/kg Se as Na2SeO3 or Nano-Se,respectively.The results were as follows:(1)The growth performance of pigs remained steady at the peak value at a concentration range of 0.2～0.5 mg/kg for Na2SeO3.Supplementation with 1.0 mg/kg Se as Na2SeO3 reduced(P0.05) growth performance as compared with the addition of a concentration range of 0.2～0.4 mg/kg Se.There were no difference in performance between the treatments of Nano-Se and Na2SeO3 when the added concentration of Se was 0.1～0.3 mg/kg.The chicks had higher(P0.05) growth performance at a concentration range of 0.4～1.0 mg/kg as Nano-Se than Na2SeO3.(2)There were no difference in serum IgG and IgM,IgM PFC,Phagocytic ratio of macrophage,natural kill cell activity between the treatments of Nano-Se and Na2SeO3 when the added concentration of Se was 0.1～0.3 mg/kg.The above immune indexes were higher(P0.05) at a concentration range of 0.4～1.0 mg/kg as Nano-Se than Na2SeO3.(4)Supplentation with Se increased the immune organs index and serum IgA,however,the increased extent was not affected by Se sources or the added concentration of Se.The results implicated that for the best concentration range of Weinberg curve,Nano-Se is wider than Na2SeO3.