Ruthenium-catalyzed C–H bond functionalization in cascade and one-pot transformations

Abstract Ruthenium complexes are well known as remarkable pre-catalysts for challenging C–H bond functionalizations. Combining them with other types of chemical reactions in a tandem or one-pot fashion is appealing from a sustainable point of view because it gives access to new strategies to diminish steps devoted to purification and isolation of (sometimes unstable) intermediates. This non-exhaustive review highlights the different approaches enabling these technologies with a particular focus on the understanding for the compatibility of the different reaction sequences. More precisely, ruthenium-catalyzed C–H bond functionalization turned out to be compatible with several organic transformations, metal-mediated reactions and transition metal catalysis.