The use of dibunol for stimulating reparative processes in the cardiac muscle in myocardial infarct in rats

: The effects of dibunol (30 mg/kg) and inosie-F (40 mg/kg) on the cardiac muscle reparation were studied on 162 coronary artery ligated rats. The long-term administration (30 days) both of dibunol and inosie-F increased the rate of collagen synthesis in the infarction area. Dibunol averted the development of the left ventricular pump failure, while inosie-F didn't prevent the postinfarction depression of cardiac contractility.