3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates-fast access to a heterocyclic scaffold for HIV-1 integrase inhibitors
2008
Abstract An efficient and reliable synthesis of the heterocyclic scaffold methyl-3-hydroxy-4-oxo-4 H -pyrido[1,2- a ]pyrimidine-2-carboxylate is described. The scope of the synthesis regarding the introduction of substituents on the pyrido-fused ring is explored.
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