hybrid genes intended for use in the production of cytotoxic T cells independent T helper cell.

SUPPLIED recombinant vectors that respond proliferative activated lymphocytes, cytotoxic T lymphocytes MAINLY WITH AN INDEPENDENCE ameliorated Th cells. The vectors comprise a region encoding a polypeptide FACTOR stimulatory operably linked to a heterologous transcriptional control region. Polypeptide expression stimulating factor from the polynucleotide RECOMBINANT ACTIVATED lymphocyte proliferative response OFFERS SMALL DEPENDENCE SUB {T cells, H} LYMPHOCYTE. WHEN lymphocyte activated by antigen-binding transcriptional control REGION CAUSES THE REGION transcribing codifying stimulating factor. Cells containing the vector, PARTICULARLY CTLS are useful in immunotherapy.