Genistein and Its Role in Regulation of AP-1 in Colorectal Cancer
2017
Colorectal cancer (CRC) is a prominent source of cancer-related deaths across the world. AP-1 is involved in CRC growth and metastasis. AP-1 is a transcription factor that regulates many oncogenic transduction pathways. In the current chapter, we discuss the importance of AP-1 on CRC growth and metastasis. Additionally, we discuss the mechanism of genistein, a tyrosine kinase inhibitor, and its effect on CRC treatment.
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