Synthesis, characterization, and antibacterial activity of a cobalt(II) Schiff base complex derived from pyridoxal and sulfanilic acid

Reaction of pyridoxal hydrochloride and sul- fanilic acid with CoCl2 in aqueous methanol solution afforded a Co(II) Schiff base complex, which was char- acterized by physico-chemical and spectroscopic methods. The structure of the complex was determined by single crystal X-ray diffraction. In the complex, the Co(II) is sandwiched at the edge of two parallel Schiff base ligands, being coordinated by two phenolic O and two imine N atoms of two Schiff base ligands plus two O atoms of water ligands, forming a distorted octahedral coordination envi- ronment. Thermal stability measurements showed that the skeleton of the complex is stable up to 500 K. The anti- bacterial activity of the complex was screened using the paper disc diffusion method.