Asymmetric Synthesis of the Quinolizidine Alkaloid (‐)‐Epimyrtine with Intramolecular Mannich Cyclization and N‐Sulfinyl δ‐Amino β‐Ketoesters.

A concise, six-step, enantioselective synthesis of (-)-epimyrtine employing the N-sulfinyl delta-amino beta-ketoester chiral building block is described.