Array substrate and manufacture method thereof, display panel and display device

The invention discloses an array substrate and a manufacture method thereof, a display panel and a display device, and belongs to the field of display technology. The array substrate comprises a substrate body, a source-drain metal layer and a first passivation metal protection layer are successively formed on the substrate body, the source-drain metal layer comprises a source electrode and a drain electrode which does not make contact with the source electrode, a conductive protection layer is formed at the position, where the first passivation metal protection layer is formed, of the substrate body, a pixel electrode is formed at the position, where the conductive protection layer is formed, of the substrate body, and the pixel electrode makes contact with the conductive protection layer. The problem that the resistance between the pixel electrode and the drain electrode is high when the first passivation metal protection layer is etched is solved, the resistance between the pixel electrode and the drain electrode is ensured, and the array substrate can be applied to the display device.