Coronary Artery Disease and Systemic Vasculitis: Case Report and Review

Chronic systemic inflammation and immune dysregulation, as a consequence of primary or secondary vasculitis, has been emphasized in pathogenesis of coronary artery disease. (Gasparyan & Ugurlucan, 2008; Mukhtyar et al., 2009; Turesson et al., 2008). Severe coronary artery disease in absence of obvious serious risk factors, especially in young age, remains a challenge to modern cardiology. In these cases, possible relation of ischemic heart disease to systemic vasculitis or thrombophilic predisposition should be also examined. (Kaplan 2009; Knockaert 2007; Tenedios et al., 2006).