CLIC4/Arf6 Pathway: A New Lead in BMPRII Inhibition in Pulmonary Hypertension

Vahitha B. Abdul-Salam,Giusy Russomanno,Chen Chien-Nien,Abdul S. Mahomed,Luke A. Yates,Martin R. Wilkins,Lan Zhao,Magdalena Gierula,Oliver Dubois,Ute Schaeper,Jens Endruschat,Beata Wojciak-Stothard

CLIC4/Arf6 Pathway: A New Lead in BMPRII Inhibition in Pulmonary Hypertension

2019

Vahitha B. Abdul-Salam
Giusy Russomanno
Chen Chien-Nien
Abdul S. Mahomed
Luke A. Yates
Martin R. Wilkins
Lan Zhao
Magdalena Gierula
Oliver Dubois
Ute Schaeper
Jens Endruschat
Beata Wojciak-Stothard

Rationale: Increased expression of CLIC4 (chloride intracellular channel 4) is a feature of endothelial dysfunction in pulmonary arterial hypertension, but its role in disease pathology is not fully understood.

Keywords:

Biology
Diabetes mellitus
Internal medicine
Pulmonary hypertension
CLIC4
Cardiology

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