L-Asparginase toxicity profile at a tertiary care hematology centre in kashmir – 10 year experience.

Purpose: To study overall incidence of adverse effects, highlight incidence of life threatening complications, identify unusual complication if any and possible measures to prevent them.Materials and methods: This was a ten year retrospective study where in data related to patients at presentation and data related to complications was taken from regional cancer registry and was compiled.Conclusion:Asparaginase is aessential  component of acute leukemia  protocols . The ability to rapidly identify and manage asparaginase-associated toxicity will help ensure patients receive the maximal benefit from asparaginase therapy.