Study on the interaction behavior of catalase with cephalosporins by chemiluminescence with flow injection analysis

The interaction behavior of catalase with cephalosporins was first studied using luminol as luminescence probe. By chemiluminescence model of protein–drug interaction in flow injection system, the binding parameters of catalase with cephalosporins were obtained, giving the binding ability of cephalosporins to catalase and the thermodynamic parameters of catalase/cephalosporins association process.