2109 Primary radiation therapy or surgery combined or not to radiation therapy in the management of squamous cell carcinoma of the penis

Purpose: To assess the prognostic factors and the outcome in patients with squamqus cell carcinoma of the penis. Mat&z/s & Mefhods: A retrospective review of 41 consecutive patients with non-metastatic invasive carcinoma of the penis, treated between 1962 and 1994, was perforrr~ed. The median age was 59 years (range: 35-76). Eight (20%) patients were circumcised, 30 (73%) were. married, and only 2 (5%) had a history of venereal disease. Existence of a penile mass was the. fast symptom in 32 (78%) patients. The anatomic site was distributed as follows: glans in 17 (41%). prepuce in 9 (22%). shaft in 8 (20%). coronary IwaIization in 4 (10%). prepuce and glans in 2 (5%). and shaft and prepuce in 1 (2%). According to UICC staging, there were 12 (29%) Tl, 24 (59%) T2.4 (10%) ‘B, and 1 TX (2%) tumors. The N-stage was distributed as foIlows: 29 (71%) patients with NO, 8 (20%) with Nl, 3 (7%) with N2, and 1(2%) with M. Ihin (32%) patients had grade 1. 7 grade 2, and 9 grade 3 hmmrs (grade was determined in 12). Fatty-four percent (n = 18) of the patients underwent a curative surgery: partial penectomy with (n = 4) or without (n = 12) lymph node dissection. or total penectomy with (n = 1) or without (n = 1) lymph node dissection. AI1 but 4 patients (operated) underwent primary (n = 23) or postoperative (n = 14) radiotherapy to the penis and inguinal lymph nodes (n = 20). penis alone (n = 9), or inguinal lymph nodes alone (n = 8). The median and mean follow-uo oeriod was 70 and 96 months. resoectivelv (ranee: 20-3311. 1.0 __