The effect of radical gastrectomy plus Roux-en-Y digestive tract reconstruction on accompanying type 2 diabetes mellitus

Objective To evaluate the curative effect of laparoscopic radical gastrectomy combined with Roux-en-Y reconstruction of the digestive tract in treatment of advanced gastric cancer complicated with type 2 diabetes mellitus. Methods 73 advanced gastric cancer complicated with type 2 diabetes mellitus patients between May 2014 to May 2016 underwent distal partial gastrectomy or total gastrectomy with Roux-en-Y GI reconstruction. Results Compared with preoperative data, postoperative level at after 1 month and 3 months were respectively for FPG (14.9±1.9 vs. 8.7±0.9, 8.8±0.9) mmol/L, OGTT 2 h PG (15.4±1.8 vs. 8.68±0.9, 8.7±0.9) mmol/L, HbA1 (10.4%±0.8% vs. 7.4%±0.6%, 7.4±0.6), BMI (29.9±1.2 vs. 25.4±0.7, 25.2±0.6) kg/m2, TC (8.4±0.6 vs. 6.7±0.6, 6.7±0.4) mmol/L and TG (2.53±0.53 vs. 1.86±0.27, 1.91±0.33) mmol/L (with all P<0.05). Conclusion Laparoscopic radical gastrectomy combined with Roux-en-Y reconstruction of the digestive tract for advanced gastric cancer significantly improves patients′ co-occurring. Key words: Stomach neoplasm; Diabetes mellitus, type 2; Gastrectomy; Anastomosis, Roux-en-Y