Juvenile Xanthogranuloma (Nevoxanthoendothelioma, JXG)

Juvenile xanthogranuloma is a rare and benign skin lesion.[1] This disorder is the most common form of non-Langerhans cell histiocytosis.[2] These lesions can occur at any age. However, they are most commonly seen in infants and small children.[3] Typically, the clinical presentation consists of solitary or multiple yellow-brown skin nodules found on the face and neck.[3] Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute. However, some cases present at noncutaneous sites and can result in serious complications.[1] As opposed to other xanthomatous diseases, juvenile xanthogranulomas are not associated with metabolic or lipid disorders.[3]