Mesotelioma pleural sarcomatoide, con diseminación masiva a peritoneo y pericardio. Un caso de autopsia

El mesotelioma maligno es una neoplasia originada a partir de las celulas mesoteliales de las membranas serosas (pleura, peritoneo, pericardio y otros). Es 5 veces mas frecuente en la cavidad pleural que en la peritoneal, y puede observarse en ambas por extension directa a traves del diafragma(1). Se presenta el caso de autopsia en una mujer de 83 anos, sin antecedentes de exposicion al asbesto, oligosintomatica, con mesotelioma pleural maligno tipo sarcomatoide, en estadio avanzado (Estadio IV). El mesotelioma es una neoplasia letal, su diagnostico a veces resulta dificultoso debido al crecimiento lento, las manifestaciones clinicas tardias y el diagnostico en estadios avanzados. En primer lugar debe descartarse secundarismo y ante clinica e imagenes compatibles debe plantearse su diagnostico. Malignant mesotheliomas are tumors derived from mesothelial cells that form the serous membranes. The incidence of mesotheliomas show a rate 5 times greater in the pleural cavity than in the peritoneum; but they can be detected in both, as a result of direct invasion through the diaphragm. A case out from an autopsy is reported, of a 83 years old female patient, with no previous history of exposure to asbestos, oligosymptomatic, with malignant pleural mesothelioma of sarcomatoideal type, at an advanced stage (Stage IV). Malignant mesotheliomas are relatively rare being a highly lethal neoplasia its diagnosis is sometimes difficult because the have a gradual development and growth, with late clinical manifestions, and with diagnosis at an advanced evolutive stages. First of all, secondarism must be discarged, and in presence of compatibles images, its diagnosis must be hypothesized.