Interleukin-6 concentrations in the vitreous body of patients with retinal detachment.

Abstract Objective To measure interleukin-6 (IL-6) levels in the vitreous body of patients with retinal detachment (RD). Patients and methods Undiluted vitreous samples were obtained from 40 patients with no history of prior vitreous or intraocular surgery. Patients were divided into two groups: A (n = 20) patients with RD and B (n = 20) patients with pre-retinal macular membranes and macular holes. IL-6 was determined using radioimmunoassay. Results IL-6 vitreous concentration in group A was 122.4 ± 16 pg/mL (range 91.5–620) and in group B was 46 ± 23 pg/mL (range 3–150) ( p Conclusions These results show that the concentration of IL-6 in the vitreous body was significantly higher in patients with RD than in the control group.