원저 ; Sulfisomidine배합 산성고자당액상배지검사의 우식예측 타당도

Objectives: The purpose of this study was to evaluate the caries prediction validity and between-observer reliability of caries activity tests using sulfisomidine-containing acidic high sucrose liquid medium (SAHS test). Methods: This longitudinal follow-up study was done for 1 year. The subjects were 188 elementary school children. The caries experience and caries activity of each of the subjects was examined. We adopted both the SAHS test and Dentocult SM test as caries activity tests. We conducted an ROC analysis on the test data, and thereafter calculated the sensitivity, specificity, predictive value, and Kappa statistics. Results: According to the ROC analysis, it was found that both the SAHS test and Dentocult SM test showed a similar level of AUC (0.5 or higher), which means that both tests have significant caries prediction validity. When the validating criterion was based on 1 or more new caries lesions and the screening criterion was based on a score of 5, it was found that the SAHS test (12 grade) showed a sensitivity value of 0.72-0.73, specificity value of 0.48-0.51, positive predictive value of 0.62-0.63, and negative predictive value of 0.61-0.62, respectively. Based on these 4 values, it was found that the SAHS test had a higher grade of sensitivity and negative predictive value than the Dentocult SM test. However, the latter had a higher grade of specificity and positive predictive value. Despite this, there were no significant differences between both tests. The SAHS test had higher between-observer reliability (kappa value) than the Dentocult SM test (0.90>0.88). Conclusions: In this study, it was found that both the SAHS test and Dentocult SM test had a similar level of caries prediction validity and between-observer reliability.