Two Novel Abietane Diterpenoids from Illicium wardii A.C.Sm.

Two novel abietane diterpenoids, wardinols A and B (1 and 2, resp.), together with five known diterpenoids, 3–7, were isolated from the fruits of Illicium wardii A.C.Sm. Their structures were elucidated on the basis of intensive spectroscopic analysis, including 1D- and 2D-NMR spectroscopy. Wardinol A (1) is a rare 9,10-epoxy-9,10-secoabietane diterpenoid. All of the isolated compounds were evaluated for their cytotoxicities against three human tumor cell lines, A549, HCT116, and CCRF-CEM.