[The inhibition of the electrophoretic-mobility-test: an in vitro assay for the estimation of activities in anti-lymphokine and anti-lymphocyte sera (author's transl)].

: Human purified lymphocytes from peripheral blood were stimulated by Con A and the concentrated supernatants were used to induce antibodies in rabbits. These anti-lymphokine immune sera were able to inhibit the electrophoretic-mobility-test (EMT) which was performed using supernatants of lymphocytes stimulated by Con A and tanned sheep red blood cells as indicator particles. Since the inhibition is strongly dose dependent the test system appears to demonstrate and compare anti-lymphokine activities in different sera. When anti-human lymphocyte globulin (Dessau, DDR) was tested in the same test system these sera had the capacity to inhibit the EMT completely.