PML-RARα and Its Phosphorylation Regulate PML Oligomerization and HIPK2 Stability

Yutaka Shima,Yuki Honma,Issay Kitabayashi

PML-RARα and Its Phosphorylation Regulate PML Oligomerization and HIPK2 Stability

2013

Yutaka Shima
Yuki Honma
Issay Kitabayashi

These findings offer mechanistic insights into the basis for the most common prodifferentiation therapies used to treat acute promyelocytic leukemia in the clinic.

Keywords:

Phosphorylation
Molecular biology
Cancer research
Acute promyelocytic leukemia
Medicine
pml rarα

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