O12.3 The Netherlands on track to achieve UNAIDS’ ‘95–95–95’ HIV targets for 2025 in all STI surveillance regions

Background On a national level, the Netherlands is closing in on the ambitious 95–95–95 HIV targets set by UNAIDS for 2025. Here, we investigated to what extent this is also the case on a regional level. Methods From the ATHENA national HIV cohort, we retrieved data about all individuals with an HIV-1 infection living in each of the eight sexually transmitted infection (STI) public health surveillance regions in the Netherlands. Based on those newly-diagnosed during 2002–2019 data, we estimated the number of people remaining undiagnosed by the end of 2019, using ECDC’s HIV Modelling Tool, a CD4 count-based back-calculation method. We subsequently estimated a four-stage HIV care continuum: (i) living with HIV, including those undiagnosed, (ii) diagnosed, (iii) in care and on antiretroviral treatment (ART), and (iv) with viral suppression (HIV RNA Results The estimated number living with HIV nationwide by the end of 2019 was 23,560 (95% confidence interval [CI] 23,370–23,820), or 135 (134–137) per 100,000 population; approximately 1,770 (1,570–2,030) were still undiagnosed. Numbers living with HIV per 100,000 population were highest in Noord-Holland/Flevoland (273, 95%CI 270–276), Zuid-Holland Noord (164, 159–171), and Zuid-Holland Zuid (144, 142–149), which include the three largest cities Amsterdam, The Hague, and Rotterdam. Across the eight regions, 90%-95% had been diagnosed, 92%-96% of those diagnosed were on ART, and 95%-98% of those on ART had a suppressed viral load. Conclusion All STI surveillance regions are on track of achieving UNAIDS’ 95–95–95 2025 targets. Increased efforts are necessary to reduce the undiagnosed population and the number of individuals not retained in care and on treatment.